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This orthogroup contains 1,362 genes from 121 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,362 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24293 | CYTOCHROME P450 FAMILY 46 SUBFAMILY A | 1229 / 1,362 | 90.2% | 99.9% of 1,230 | ≥80% support |
| Pfam | PF00067 | p450 | 1217 / 1,362 | 89.4% | 100.0% of 1,217 | ≥80% support |
| GO | GO:0004497 Molecular Function | monooxygenase activity | 1233 / 1,362 | 90.5% | 100.0% of 1,233 | ≥80% support |
| GO | GO:0005506 Molecular Function | iron ion binding | 1233 / 1,362 | 90.5% | 100.0% of 1,233 | ≥80% support |
| GO | GO:0016705 Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 1233 / 1,362 | 90.5% | 100.0% of 1,233 | ≥80% support |
| GO | GO:0020037 Molecular Function | heme binding | 1233 / 1,362 | 90.5% | 100.0% of 1,233 | ≥80% support |
| GO | GO:0006707 Biological Process | cholesterol catabolic process | 1229 / 1,362 | 90.2% | 99.7% of 1,233 | ≥80% support |
| GO | GO:0033781 Molecular Function | cholesterol 24-hydroxylase activity | 1229 / 1,362 | 90.2% | 99.7% of 1,233 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0007.g51.t1 | XP_029187372.2 | cholesterol 24-hydroxylase-like [Acropora millepora] | Q9WVK8 Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46 | JBrowse |
| Acropora microphthalma | amic_s0007.g52.t1 | XP_015767897.1 | PREDICTED: cholesterol 24-hydroxylase-like isoform X1 [Acropora digitifera] | Q9WVK8 Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46 | JBrowse |
| Acropora microphthalma | amic_s0116.g81.t1 | XP_015761827.1 | PREDICTED: cholesterol 24-hydroxylase-like [Acropora digitifera] | Q9Y6A2 Cholesterol 24-hydroxylase OS=Homo sapiens OX=9606 GN=CYP46A | JBrowse |
| Acropora microphthalma | amic_s0295.g47.t1 | XP_015757888.1 | PREDICTED: cholesterol 24-hydroxylase-like [Acropora digitifera] | Q9WVK8 Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46 | JBrowse |
| Acropora microphthalma | amic_s1891.g1.t1 | XP_029187374.2 | cholesterol 24-hydroxylase-like [Acropora millepora] | Q9WVK8 Cholesterol 24-hydroxylase OS=Mus musculus OX=10090 GN=Cyp46 | JBrowse |
| Acropora microphthalma | amic_s2421.g1.t1 | XP_015757888.1 | PREDICTED: cholesterol 24-hydroxylase-like [Acropora digitifera] | – | JBrowse |
