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This orthogroup contains 829 genes from 139 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 829 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11844 | METALLOPROTEASE INHIBITOR | 738 / 829 | 89.0% | 100.0% of 738 | ≥80% support |
| Pfam | PF00965 | TIMP — Tissue inhibitor of metalloproteinase | 744 / 829 | 89.8% | 100.0% of 744 | ≥80% support |
| GO | GO:0008191 Molecular Function | metalloendopeptidase inhibitor activity | 744 / 829 | 89.8% | 100.0% of 744 | ≥80% support |
| GO | GO:0002020 Molecular Function | protease binding | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0005615 Cellular Component | extracellular space | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0010033 Biological Process | obsolete response to organic substance | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0010951 Biological Process | negative regulation of endopeptidase activity | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0031012 Cellular Component | extracellular matrix | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0051045 Biological Process | negative regulation of membrane protein ectodomain proteolysis | 635 / 829 | 76.6% | 85.4% of 744 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 598 / 829 | 72.1% | 80.4% of 744 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0003.g138.t1 | XP_029208256.2 | metalloproteinase inhibitor 3-like [Acropora millepora] | – | JBrowse |
| Acropora microphthalma | amic_s0003.g141.t1 | XP_015767278.1 | PREDICTED: metalloproteinase inhibitor 3-like [Acropora digitifera] | – | JBrowse |
| Acropora microphthalma | amic_s0003.g149.t1 | XP_029197268.1 | metalloproteinase inhibitor 1-like [Acropora millepora] | P39876 Metalloproteinase inhibitor 3 OS=Mus musculus OX=10090 GN=Ti | JBrowse |
| Acropora microphthalma | amic_s0003.g150.t1 | XP_015767265.1 | PREDICTED: metalloproteinase inhibitor 3-like [Acropora digitifera] | Q9W6B4 Metalloproteinase inhibitor 3 OS=Scyliorhinus torazame OX=75 | JBrowse |
| Acropora microphthalma | amic_s0101.g107.t1 | XP_015778164.1 | PREDICTED: uncharacterized protein LOC107356046 [Acropora digitifera] | – | JBrowse |
