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This orthogroup contains 405 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 405 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10150 | DNA REPAIR ENDONUCLEASE XPF | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0000014 Molecular Function | single-stranded DNA endodeoxyribonuclease activity | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0000110 Cellular Component | nucleotide-excision repair factor 1 complex | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0000712 Biological Process | resolution of meiotic recombination intermediates | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0003684 Molecular Function | damaged DNA binding | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:0006296 Biological Process | obsolete nucleotide-excision repair, DNA incision, 5'-to lesion | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| GO | GO:1901255 Biological Process | nucleotide-excision repair involved in interstrand cross-link repair | 355 / 405 | 87.7% | 99.7% of 356 | ≥80% support |
| Pfam | PF02732 | ERCC4 | 224 / 405 | 55.3% | 97.8% of 229 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 225 / 405 | 55.6% | 63.2% of 356 | ≥50% support |
| GO | GO:0004518 Molecular Function | nuclease activity | 224 / 405 | 55.3% | 62.9% of 356 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0050.g108.t1 | XP_029184843.2 | LOW QUALITY PROTEIN: DNA repair endonuclease XPF-like [Acropora millepora] | Q92889 DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 | JBrowse |
