← Back to the gene family browser
This orthogroup contains 336 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 336 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 243 / 336 | 72.3% | 85.6% of 284 | ≥50% support |
| Pfam | PF00617 | RasGEF | 236 / 336 | 70.2% | 86.5% of 273 | ≥50% support |
| Pfam | PF00788 | RA | 204 / 336 | 60.7% | 74.7% of 273 | ≥50% support |
| Pfam | PF00618 | RasGEF_N — RasGEF N-terminal motif | 202 / 336 | 60.1% | 74.0% of 273 | ≥50% support |
| Pfam | PF00595 | PDZ | 191 / 336 | 56.9% | 70.0% of 273 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 255 / 336 | 75.9% | 92.7% of 275 | ≥50% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 250 / 336 | 74.4% | 90.9% of 275 | ≥50% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 250 / 336 | 74.4% | 90.9% of 275 | ≥50% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 243 / 336 | 72.3% | 88.4% of 275 | ≥50% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 243 / 336 | 72.3% | 88.4% of 275 | ≥50% support |
| GO | GO:0016324 Cellular Component | apical plasma membrane | 239 / 336 | 71.1% | 86.9% of 275 | ≥50% support |
| GO | GO:0007165 Biological Process | signal transduction | 227 / 336 | 67.6% | 82.6% of 275 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 204 / 336 | 60.7% | 74.2% of 275 | ≥50% support |
| KEGG | K08018 | RAPGEF2, PDZGEF1 — Tight junction | 172 / 336 | 51.2% | 95.6% of 180 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0014.g154.t1 | XP_029186931.2 | rap guanine nucleotide exchange factor 6-like [Acropora millepora] | F1M386 Rap guanine nucleotide exchange factor 2 OS=Rattus norvegicu | JBrowse |
| Acropora microphthalma | amic_s0014.g154.t2 | XP_029186931.2 | rap guanine nucleotide exchange factor 6-like [Acropora millepora] | F1M386 Rap guanine nucleotide exchange factor 2 OS=Rattus norvegicu | JBrowse |
