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This orthogroup contains 331 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 331 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11136 | FOLYLPOLYGLUTAMATE SYNTHASE-RELATED | 269 / 331 | 81.3% | 98.9% of 272 | ≥80% support |
| GO | GO:0004326 Molecular Function | tetrahydrofolylpolyglutamate synthase activity | 272 / 331 | 82.2% | 99.6% of 273 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 272 / 331 | 82.2% | 99.6% of 273 | ≥80% support |
| GO | GO:0009058 Biological Process | biosynthetic process | 272 / 331 | 82.2% | 99.6% of 273 | ≥80% support |
| GO | GO:0009396 Biological Process | folic acid-containing compound biosynthetic process | 272 / 331 | 82.2% | 99.6% of 273 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 270 / 331 | 81.6% | 98.9% of 273 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 263 / 331 | 79.5% | 96.3% of 273 | ≥50% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 262 / 331 | 79.2% | 96.0% of 273 | ≥50% support |
| GO | GO:0046901 Biological Process | tetrahydrofolylpolyglutamate biosynthetic process | 262 / 331 | 79.2% | 96.0% of 273 | ≥50% support |
| GO | GO:0016881 Molecular Function | acid-amino acid ligase activity | 248 / 331 | 74.9% | 90.8% of 273 | ≥50% support |
| KEGG | K01930 | FPGS — Antifolate resistance | 203 / 331 | 61.3% | 97.1% of 209 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0064.g56.t1 | XP_044174437.1 | folylpolyglutamate synthase, mitochondrial-like isoform X1 [Acropora millepora] | A6H751 Folylpolyglutamate synthase, mitochondrial OS=Bos taurus OX= | JBrowse |
