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This orthogroup contains 316 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 316 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 256 / 316 | 81.0% | 95.9% of 267 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 269 / 316 | 85.1% | 97.8% of 275 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 268 / 316 | 84.8% | 97.5% of 275 | ≥80% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 268 / 316 | 84.8% | 97.5% of 275 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 261 / 316 | 82.6% | 94.9% of 275 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 256 / 316 | 81.0% | 93.1% of 275 | ≥80% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 256 / 316 | 81.0% | 93.1% of 275 | ≥80% support |
| GO | GO:0032301 Cellular Component | MutSalpha complex | 254 / 316 | 80.4% | 92.4% of 275 | ≥80% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 218 / 316 | 69.0% | 80.2% of 272 | ≥50% support |
| Pfam | PF05192 | MutS_III — MutS domain III | 201 / 316 | 63.6% | 73.9% of 272 | ≥50% support |
| Pfam | PF01624 | MutS_I — MutS domain I | 197 / 316 | 62.3% | 72.4% of 272 | ≥50% support |
| Pfam | PF05190 | MutS_IV — MutS family domain IV | 196 / 316 | 62.0% | 72.1% of 272 | ≥50% support |
| Pfam | PF05188 | MutS_II — MutS domain II | 190 / 316 | 60.1% | 69.9% of 272 | ≥50% support |
| KEGG | K08737 | MSH6 — DNA repair and recombination proteins | 169 / 316 | 53.5% | 94.9% of 178 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0295.g19.t1 | XP_044184150.1 | DNA mismatch repair protein Msh6-like isoform X1 [Acropora millepora] | E1BYJ2 DNA mismatch repair protein Msh6 OS=Gallus gallus OX=9031 GN | JBrowse |
| Acropora microphthalma | amic_s0295.g19.t2 | XP_044184151.1 | DNA mismatch repair protein Msh6-like isoform X2 [Acropora millepora] | E1BYJ2 DNA mismatch repair protein Msh6 OS=Gallus gallus OX=9031 GN | JBrowse |
| Acropora microphthalma | amic_s1755.g1.t1 | XP_044184295.1 | DNA mismatch repair protein Msh6-like isoform X2 [Acropora millepora] | E1BYJ2 DNA mismatch repair protein Msh6 OS=Gallus gallus OX=9031 GN | JBrowse |
