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This orthogroup contains 308 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 308 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0005524 Molecular Function | ATP binding | 261 / 308 | 84.7% | 100.0% of 261 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 261 / 308 | 84.7% | 100.0% of 261 | ≥80% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 261 / 308 | 84.7% | 100.0% of 261 | ≥80% support |
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 241 / 308 | 78.3% | 99.2% of 243 | ≥50% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 213 / 308 | 69.2% | 82.2% of 259 | ≥50% support |
| Pfam | PF05192 | MutS_III — MutS domain III | 202 / 308 | 65.6% | 78.0% of 259 | ≥50% support |
| Pfam | PF05190 | MutS_IV — MutS family domain IV | 196 / 308 | 63.6% | 75.7% of 259 | ≥50% support |
| Pfam | PF05188 | MutS_II — MutS domain II | 185 / 308 | 60.1% | 71.4% of 259 | ≥50% support |
| Pfam | PF01624 | MutS_I — MutS domain I | 180 / 308 | 58.4% | 69.5% of 259 | ≥50% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 241 / 308 | 78.3% | 92.3% of 261 | ≥50% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 241 / 308 | 78.3% | 92.3% of 261 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 236 / 308 | 76.6% | 90.4% of 261 | ≥50% support |
| GO | GO:0006312 Biological Process | mitotic recombination | 236 / 308 | 76.6% | 90.4% of 261 | ≥50% support |
| GO | GO:0032301 Cellular Component | MutSalpha complex | 236 / 308 | 76.6% | 90.4% of 261 | ≥50% support |
| KEGG | K08735 | MSH2 — DNA repair and recombination proteins | 196 / 308 | 63.6% | 95.2% of 206 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0013.g70.t1 | XP_029196703.2 | DNA mismatch repair protein Msh2-like [Acropora millepora] | P43246 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN= | JBrowse |
