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🧬 OG0003734

This orthogroup contains 279 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 87.1%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 279 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10139DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11243 / 27987.1%98.8%
of 246		≥80% support
PfamPF04152Mre11_DNA_bind — Mre11 DNA-binding presumed domain227 / 27981.4%93.0%
of 244		≥80% support
GOGO:0000723
Biological Process		telomere maintenance243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0097552
Biological Process		mitochondrial double-strand break repair via homologous recombination243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0042138
Biological Process		meiotic DNA double-strand break formation243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0035861
Cellular Component		site of double-strand break243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0030870
Cellular Component		Mre11 complex243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0007095
Biological Process		mitotic G2 DNA damage checkpoint signaling243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0006303
Biological Process		double-strand break repair via nonhomologous end joining243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0000724
Biological Process		double-strand break repair via homologous recombination243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0000014
Molecular Function		single-stranded DNA endodeoxyribonuclease activity243 / 27987.1%98.4%
of 247		≥80% support
GOGO:0031573
Biological Process		mitotic intra-S DNA damage checkpoint signaling238 / 27985.3%96.4%
of 247		≥80% support
GOGO:0006302
Biological Process		double-strand break repair230 / 27982.4%93.1%
of 247		≥80% support
GOGO:0005634
Cellular Component		nucleus228 / 27981.7%92.3%
of 247		≥80% support
GOGO:0030145
Molecular Function		manganese ion binding227 / 27981.4%91.9%
of 247		≥80% support
GOGO:0004519
Molecular Function		endonuclease activity227 / 27981.4%91.9%
of 247		≥80% support
PfamPF00149Metallophos — Calcineurin-like phosphoesterase216 / 27977.4%88.5%
of 244		≥50% support
GOGO:0016787
Molecular Function		hydrolase activity216 / 27977.4%87.5%
of 247		≥50% support
GOGO:0008296
Molecular Function		3'-5'-DNA exonuclease activity205 / 27973.5%83.0%
of 247		≥50% support
GOGO:0004520
Molecular Function		DNA endonuclease activity205 / 27973.5%83.0%
of 247		≥50% support
KEGGK10865MRE11 — DNA repair and recombination proteins202 / 27972.4%97.6%
of 207		≥50% support
📊 Total members in OG0003734: 1 (filtered to AMICR · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Acropora microphthalmaamic_s0023.g141.t1XP_029187689.2LOW QUALITY PROTEIN: double-strand break repair protein MRE11-like [Acropora millepora]Q9W6K1
Double-strand break repair protein MRE11 OS=Xenopus laevis O		JBrowse
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