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This orthogroup contains 271 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 271 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12124 | POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED | 219 / 271 | 80.8% | 96.9% of 226 | ≥80% support |
| GO | GO:0000176 Cellular Component | nuclear exosome (RNase complex) | 224 / 271 | 82.7% | 95.7% of 234 | ≥80% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 222 / 271 | 81.9% | 94.9% of 234 | ≥80% support |
| GO | GO:0000175 Molecular Function | 3'-5'-RNA exonuclease activity | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071051 Biological Process | poly(A)-dependent snoRNA 3'-end processing | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071044 Biological Process | histone mRNA catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071040 Biological Process | nuclear polyadenylation-dependent antisense transcript catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071039 Biological Process | nuclear polyadenylation-dependent CUT catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071038 Biological Process | TRAMP-dependent tRNA surveillance pathway | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071037 Biological Process | nuclear polyadenylation-dependent snRNA catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071036 Biological Process | nuclear polyadenylation-dependent snoRNA catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0071035 Biological Process | nuclear polyadenylation-dependent rRNA catabolic process | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0005730 Cellular Component | nucleolus | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0003727 Molecular Function | single-stranded RNA binding | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| GO | GO:0000467 Biological Process | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 219 / 271 | 80.8% | 93.6% of 234 | ≥80% support |
| Pfam | PF01612 | DNA_pol_A_exo1 — 3'-5' exonuclease | 213 / 271 | 78.6% | 93.4% of 228 | ≥50% support |
| Pfam | PF08066 | PMC2NT | 173 / 271 | 63.8% | 75.9% of 228 | ≥50% support |
| Pfam | PF00570 | HRDC | 170 / 271 | 62.7% | 74.6% of 228 | ≥50% support |
| GO | GO:0008408 Molecular Function | 3'-5' exonuclease activity | 213 / 271 | 78.6% | 91.0% of 234 | ≥50% support |
| GO | GO:0006139 Biological Process | nucleobase-containing compound metabolic process | 213 / 271 | 78.6% | 91.0% of 234 | ≥50% support |
| GO | GO:0044237 Biological Process | obsolete cellular metabolic process | 186 / 271 | 68.6% | 79.5% of 234 | ≥50% support |
| GO | GO:0000166 Molecular Function | nucleotide binding | 186 / 271 | 68.6% | 79.5% of 234 | ≥50% support |
| GO | GO:0006396 Biological Process | RNA processing | 173 / 271 | 63.8% | 73.9% of 234 | ≥50% support |
| KEGG | K12591 | RRP6, EXOSC10 — Messenger RNA biogenesis | 168 / 271 | 62.0% | 94.4% of 178 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0114.g14.t1 | XP_029212610.2 | LOW QUALITY PROTEIN: exosome component 10-like [Acropora millepora] | Q01780 Exosome complex component 10 OS=Homo sapiens OX=9606 GN=EXOS | JBrowse |
| Acropora microphthalma | amic_s0114.g14.t2 | XP_029212610.2 | LOW QUALITY PROTEIN: exosome component 10-like [Acropora millepora] | Q01780 Exosome complex component 10 OS=Homo sapiens OX=9606 GN=EXOS | JBrowse |
