← Back to the gene family browser
This orthogroup contains 265 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 265 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11630 | DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| Pfam | PF00493 | MCM | 187 / 265 | 70.6% | 88.6% of 211 | ≥50% support |
| Pfam | PF18263 | MCM6_C — MCM6 C-terminal winged-helix domain | 179 / 265 | 67.6% | 84.8% of 211 | ≥50% support |
| Pfam | PF17207 | MCM_OB — MCM OB domain | 179 / 265 | 67.6% | 84.8% of 211 | ≥50% support |
| Pfam | PF17855 | MCM_lid — MCM AAA-lid domain | 178 / 265 | 67.2% | 84.4% of 211 | ≥50% support |
| Pfam | PF14551 | MCM_N — MCM N-terminal domain | 169 / 265 | 63.8% | 80.1% of 211 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 200 / 265 | 75.5% | 100.0% of 200 | ≥50% support |
| GO | GO:0042555 Cellular Component | MCM complex | 200 / 265 | 75.5% | 100.0% of 200 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 200 / 265 | 75.5% | 100.0% of 200 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 200 / 265 | 75.5% | 100.0% of 200 | ≥50% support |
| GO | GO:0017116 Molecular Function | single-stranded DNA helicase activity | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:0006268 Biological Process | DNA unwinding involved in DNA replication | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:1902969 Biological Process | mitotic DNA replication | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:1990518 Molecular Function | single-stranded 3'-5' DNA helicase activity | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:0003697 Molecular Function | single-stranded DNA binding | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:0000727 Biological Process | double-strand break repair via break-induced replication | 199 / 265 | 75.1% | 99.5% of 200 | ≥50% support |
| GO | GO:0006270 Biological Process | DNA replication initiation | 178 / 265 | 67.2% | 89.0% of 200 | ≥50% support |
| GO | GO:0003678 Molecular Function | DNA helicase activity | 178 / 265 | 67.2% | 89.0% of 200 | ≥50% support |
| GO | GO:0006260 Biological Process | DNA replication | 169 / 265 | 63.8% | 84.5% of 200 | ≥50% support |
| KEGG | K02542 | MCM6 — DNA replication proteins | 167 / 265 | 63.0% | 99.4% of 168 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0386.g7.t1 | XP_029182827.1 | DNA replication licensing factor MCM6-like [Acropora millepora] | Q14566 DNA replication licensing factor MCM6 OS=Homo sapiens OX=960 | JBrowse |
