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This orthogroup contains 264 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 264 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00984 | UDPG_MGDP_dh — UDP-glucose/GDP-mannose dehydrogenase family, central domain | 217 / 264 | 82.2% | 92.0% of 236 | ≥80% support |
| Pfam | PF03720 | UDPG_MGDP_dh_C — UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain | 216 / 264 | 81.8% | 91.5% of 236 | ≥80% support |
| Pfam | PF03721 | UDPG_MGDP_dh_N — UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain | 215 / 264 | 81.4% | 91.1% of 236 | ≥80% support |
| GO | GO:0003979 Molecular Function | UDP-glucose 6-dehydrogenase activity | 236 / 264 | 89.4% | 99.2% of 238 | ≥80% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 236 / 264 | 89.4% | 99.2% of 238 | ≥80% support |
| GO | GO:0051287 Molecular Function | NAD binding | 236 / 264 | 89.4% | 99.2% of 238 | ≥80% support |
| PANTHER | PTHR11374 | UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE | 197 / 264 | 74.6% | 82.8% of 238 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 196 / 264 | 74.2% | 82.4% of 238 | ≥50% support |
| GO | GO:0006024 Biological Process | glycosaminoglycan biosynthetic process | 195 / 264 | 73.9% | 81.9% of 238 | ≥50% support |
| KEGG | K00012 | UGDH, ugd — O-Antigen nucleotide sugar biosynthesis | 187 / 264 | 70.8% | 98.4% of 190 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0157.g31.t1 | XP_044178213.1 | UDP-glucose 6-dehydrogenase-like [Acropora millepora] | O70475 UDP-glucose 6-dehydrogenase OS=Mus musculus OX=10090 GN=Ugdh | JBrowse |
| Acropora microphthalma | amic_s4733.g1.t1 | XP_015748531.1 | PREDICTED: UDP-glucose 6-dehydrogenase-like [Acropora digitifera] | Q9LF33 UDP-glucose 6-dehydrogenase 3 OS=Arabidopsis thaliana OX=370 | JBrowse |