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🧬 OG0004368

This orthogroup contains 260 genes from 146 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 90.0%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 260 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11140PRE-MRNA SPLICING FACTOR PRP8234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0000398
Biological Process		mRNA splicing, via spliceosome234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0097157
Molecular Function		pre-mRNA intronic binding234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0071013
Cellular Component		catalytic step 2 spliceosome234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0030623
Molecular Function		U5 snRNA binding234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0030620
Molecular Function		U2 snRNA binding234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0030619
Molecular Function		U1 snRNA binding234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0017070
Molecular Function		U6 snRNA binding234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0005682
Cellular Component		U5 snRNP234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0005681
Cellular Component		spliceosomal complex234 / 26090.0%100.0%
of 234		≥80% support
GOGO:0000244
Biological Process		spliceosomal tri-snRNP complex assembly234 / 26090.0%100.0%
of 234		≥80% support
PfamPF12134PRP8_domainIV — PRP8 domain IV core180 / 26069.2%77.3%
of 233		≥50% support
PfamPF08083PROCN179 / 26068.9%76.8%
of 233		≥50% support
PfamPF08082PRO8NT176 / 26067.7%75.5%
of 233		≥50% support
PfamPF08084PROCT174 / 26066.9%74.7%
of 233		≥50% support
PfamPF01398JAB173 / 26066.5%74.3%
of 233		≥50% support
PfamPF10598RRM_4 — RNA recognition motif of the spliceosomal PrP8173 / 26066.5%74.3%
of 233		≥50% support
PfamPF10597U5_2-snRNA_bdg — U5-snRNA binding site 2 of PrP8171 / 26065.8%73.4%
of 233		≥50% support
PfamPF10596U6-snRNA_bdg — U6-snRNA interacting domain of PrP8170 / 26065.4%73.0%
of 233		≥50% support
GOGO:0005515
Molecular Function		protein binding175 / 26067.3%74.8%
of 234		≥50% support
GOGO:0008237
Molecular Function		metallopeptidase activity173 / 26066.5%73.9%
of 234		≥50% support
GOGO:0008233
Molecular Function		peptidase activity173 / 26066.5%73.9%
of 234		≥50% support
GOGO:0003723
Molecular Function		RNA binding173 / 26066.5%73.9%
of 234		≥50% support
KEGGK12856PRPF8, PRP8 — Spliceosome156 / 26060.0%96.3%
of 162		≥50% support
📊 Total members in OG0004368: 1 (filtered to AMICR · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Acropora microphthalmaamic_s0019.g91.t1XP_029195436.2pre-mRNA-processing-splicing factor 8 [Acropora millepora]Q6P2Q9
Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=960		JBrowse
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