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This orthogroup contains 250 genes from 116 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 250 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11361 | DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER | 210 / 250 | 84.0% | 99.5% of 211 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 225 / 250 | 90.0% | 100.0% of 225 | ≥80% support |
| GO | GO:0006298 Biological Process | mismatch repair | 225 / 250 | 90.0% | 100.0% of 225 | ≥80% support |
| GO | GO:0030983 Molecular Function | mismatched DNA binding | 225 / 250 | 90.0% | 100.0% of 225 | ≥80% support |
| GO | GO:0003690 Molecular Function | double-stranded DNA binding | 210 / 250 | 84.0% | 93.3% of 225 | ≥80% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 210 / 250 | 84.0% | 93.3% of 225 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 207 / 250 | 82.8% | 92.0% of 225 | ≥80% support |
| GO | GO:0006312 Biological Process | mitotic recombination | 207 / 250 | 82.8% | 92.0% of 225 | ≥80% support |
| Pfam | PF00488 | MutS_V — MutS domain V | 187 / 250 | 74.8% | 83.1% of 225 | ≥50% support |
| Pfam | PF05192 | MutS_III — MutS domain III | 161 / 250 | 64.4% | 71.6% of 225 | ≥50% support |
| Pfam | PF01624 | MutS_I — MutS domain I | 151 / 250 | 60.4% | 67.1% of 225 | ≥50% support |
| Pfam | PF05188 | MutS_II — MutS domain II | 135 / 250 | 54.0% | 60.0% of 225 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0069.g6.t1 | XP_015754748.1 | PREDICTED: DNA mismatch repair protein Msh3-like [Acropora digitifera] | P20585 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN= | JBrowse |
