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This orthogroup contains 243 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 243 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12066 | TELOMERASE REVERSE TRANSCRIPTASE | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0000333 Cellular Component | telomerase catalytic core complex | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0003721 Molecular Function | obsolete telomerase RNA reverse transcriptase activity | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0007004 Biological Process | telomere maintenance via telomerase | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0042162 Molecular Function | telomeric DNA binding | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| GO | GO:0070034 Molecular Function | telomerase RNA binding | 202 / 243 | 83.1% | 99.5% of 203 | ≥80% support |
| Pfam | PF12009 | Telomerase_RBD — Telomerase ribonucleoprotein complex - RNA binding domain | 161 / 243 | 66.3% | 89.0% of 181 | ≥50% support |
| Pfam | PF21399 | TERT_C — Telomerase reverse transcriptase, C-terminal extension | 132 / 243 | 54.3% | 72.9% of 181 | ≥50% support |
| GO | GO:0003964 Molecular Function | RNA-directed DNA polymerase activity | 161 / 243 | 66.3% | 79.3% of 203 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0004.g80.t1 | XP_029212267.2 | telomerase reverse transcriptase-like [Acropora millepora] | Q6A548 Telomerase reverse transcriptase OS=Canis lupus familiaris O | JBrowse |
