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Support counts the member genes carrying the term. % of genes is that count over all 240 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR43557 | APOPTOSIS-INDUCING FACTOR 1 | 204 / 240 | 85.0% | 99.0% of 206 | ≥80% support |
| Pfam | PF07992 | Pyr_redox_2 — Pyridine nucleotide-disulphide oxidoreductase | 199 / 240 | 82.9% | 96.1% of 207 | ≥80% support |
| Pfam | PF14721 | AIF_C — Apoptosis-inducing factor, mitochondrion-associated, C-term | 194 / 240 | 80.8% | 93.7% of 207 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 206 / 240 | 85.8% | 98.6% of 209 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0012501 Biological Process | programmed cell death | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0016174 Molecular Function | NAD(P)H oxidase H2O2-forming activity | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0016651 Molecular Function | oxidoreductase activity, acting on NAD(P)H | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0033108 Biological Process | mitochondrial respiratory chain complex assembly | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0071949 Molecular Function | FAD binding | 204 / 240 | 85.0% | 97.6% of 209 | ≥80% support |
| GO | GO:0006915 Biological Process | apoptotic process | 202 / 240 | 84.2% | 96.7% of 209 | ≥80% support |
| GO | GO:0046983 Molecular Function | protein dimerization activity | 194 / 240 | 80.8% | 92.8% of 209 | ≥80% support |
| GO | GO:0050660 Molecular Function | flavin adenine dinucleotide binding | 193 / 240 | 80.4% | 92.3% of 209 | ≥80% support |
| KEGG | K04727 | AIFM1, PDCD8 — Necroptosis | 178 / 240 | 74.2% | 98.3% of 181 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0031.g51.t1 | XP_015752935.1 | PREDICTED: apoptosis-inducing factor 1, mitochondrial-like [Acropora digitifera] | O95831 Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens O | JBrowse |
| Acropora microphthalma | amic_s0031.g51.t2 | XP_015752935.1 | PREDICTED: apoptosis-inducing factor 1, mitochondrial-like [Acropora digitifera] | O95831 Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens O | JBrowse |
| Acropora microphthalma | amic_s2284.g1.t1 | XP_029188016.2 | apoptosis-inducing factor 1, mitochondrial-like [Acropora millepora] | Q9Z0X1 Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus O | JBrowse |