Gene Family

← Back to the gene family browser

Member genes
240
Species
137
Sequences
240
Best annotation support
85.0%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 85.0% of the 240 members.

Support counts the member genes carrying the term. % of genes is that count over all 240 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR43557APOPTOSIS-INDUCING FACTOR 1204 / 24085.0%99.0%
of 206
≥80% support
PfamPF07992Pyr_redox_2 — Pyridine nucleotide-disulphide oxidoreductase199 / 24082.9%96.1%
of 207
≥80% support
PfamPF14721AIF_C — Apoptosis-inducing factor, mitochondrion-associated, C-term194 / 24080.8%93.7%
of 207
≥80% support
GOGO:0016491
Molecular Function
oxidoreductase activity206 / 24085.8%98.6%
of 209
≥80% support
GOGO:0005737
Cellular Component
cytoplasm204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0005739
Cellular Component
mitochondrion204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0012501
Biological Process
programmed cell death204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0016174
Molecular Function
NAD(P)H oxidase H2O2-forming activity204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0016651
Molecular Function
oxidoreductase activity, acting on NAD(P)H204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0033108
Biological Process
mitochondrial respiratory chain complex assembly204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0071949
Molecular Function
FAD binding204 / 24085.0%97.6%
of 209
≥80% support
GOGO:0006915
Biological Process
apoptotic process202 / 24084.2%96.7%
of 209
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity194 / 24080.8%92.8%
of 209
≥80% support
GOGO:0050660
Molecular Function
flavin adenine dinucleotide binding193 / 24080.4%92.3%
of 209
≥80% support
KEGGK04727AIFM1, PDCD8 — Necroptosis178 / 24074.2%98.3%
of 181
≥50% support
📊 Total members in OG0005242: 3 (filtered to AMICR · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Acropora microphthalmaamic_s0031.g51.t1XP_015752935.1PREDICTED: apoptosis-inducing factor 1, mitochondrial-like [Acropora digitifera]O95831
Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens O
JBrowse
Acropora microphthalmaamic_s0031.g51.t2XP_015752935.1PREDICTED: apoptosis-inducing factor 1, mitochondrial-like [Acropora digitifera]O95831
Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens O
JBrowse
Acropora microphthalmaamic_s2284.g1.t1XP_029188016.2apoptosis-inducing factor 1, mitochondrial-like [Acropora millepora]Q9Z0X1
Apoptosis-inducing factor 1, mitochondrial OS=Mus musculus O
JBrowse
Go to page: of 1 pages
TOP