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This orthogroup contains 238 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 238 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15735 | FCH AND DOUBLE SH3 DOMAINS PROTEIN | 203 / 238 | 85.3% | 99.5% of 204 | ≥80% support |
| GO | GO:0030833 Biological Process | regulation of actin filament polymerization | 203 / 238 | 85.3% | 99.0% of 205 | ≥80% support |
| GO | GO:0007274 Biological Process | neuromuscular synaptic transmission | 199 / 238 | 83.6% | 97.1% of 205 | ≥80% support |
| GO | GO:0031594 Cellular Component | neuromuscular junction | 199 / 238 | 83.6% | 97.1% of 205 | ≥80% support |
| GO | GO:0055037 Cellular Component | recycling endosome | 199 / 238 | 83.6% | 97.1% of 205 | ≥80% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 177 / 238 | 74.4% | 87.6% of 202 | ≥50% support |
| Pfam | PF00611 | FCH — Fes/CIP4, and EFC/F-BAR homology domain | 157 / 238 | 66.0% | 77.7% of 202 | ≥50% support |
| Pfam | PF14604 | SH3_9 — Variant SH3 domain | 121 / 238 | 50.8% | 59.9% of 202 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 182 / 238 | 76.5% | 88.8% of 205 | ≥50% support |
| KEGG | K20125 | FCHSD — Membrane trafficking | 155 / 238 | 65.1% | 98.7% of 157 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0234.g22.t1 | XP_029203221.2 | F-BAR and double SH3 domains protein 2-like [Acropora millepora] | O94868 F-BAR and double SH3 domains protein 2 OS=Homo sapiens OX=96 | JBrowse |