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This orthogroup contains 229 genes from 93 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 229 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 215 / 229 | 93.9% | 100.0% of 215 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 212 / 229 | 92.6% | 97.7% of 217 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 212 / 229 | 92.6% | 97.7% of 217 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 217 / 229 | 94.8% | 100.0% of 217 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 217 / 229 | 94.8% | 100.0% of 217 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 216 / 229 | 94.3% | 99.5% of 217 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 215 / 229 | 93.9% | 99.1% of 217 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0094.g71.t1 | XP_020621107.1 | neuronal acetylcholine receptor subunit alpha-7-like [Orbicella faveolata] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |
| Acropora microphthalma | amic_s0094.g72.t1 | XP_015772288.1 | PREDICTED: neuronal acetylcholine receptor subunit alpha-7-like [Acropora digitifera] | P22770 Neuronal acetylcholine receptor subunit alpha-7 OS=Gallus ga | JBrowse |