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This orthogroup contains 228 genes from 122 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 228 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR46239 | DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C | 189 / 228 | 82.9% | 98.4% of 192 | ≥80% support |
| GO | GO:0000400 Molecular Function | four-way junction DNA binding | 190 / 228 | 83.3% | 97.9% of 194 | ≥80% support |
| GO | GO:0005657 Cellular Component | replication fork | 190 / 228 | 83.3% | 97.9% of 194 | ≥80% support |
| GO | GO:0033065 Cellular Component | Rad51C-XRCC3 complex | 190 / 228 | 83.3% | 97.9% of 194 | ≥80% support |
| GO | GO:0000707 Biological Process | meiotic DNA recombinase assembly | 189 / 228 | 82.9% | 97.4% of 194 | ≥80% support |
| GO | GO:0007131 Biological Process | reciprocal meiotic recombination | 189 / 228 | 82.9% | 97.4% of 194 | ≥80% support |
| GO | GO:0008821 Molecular Function | crossover junction DNA endonuclease activity | 189 / 228 | 82.9% | 97.4% of 194 | ≥80% support |
| GO | GO:0033063 Cellular Component | Rad51B-Rad51C-Rad51D-XRCC2 complex | 189 / 228 | 82.9% | 97.4% of 194 | ≥80% support |
| Pfam | PF08423 | Rad51 | 181 / 228 | 79.4% | 99.5% of 182 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 181 / 228 | 79.4% | 93.3% of 194 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 181 / 228 | 79.4% | 93.3% of 194 | ≥50% support |
| GO | GO:0006281 Biological Process | DNA repair | 181 / 228 | 79.4% | 93.3% of 194 | ≥50% support |
| GO | GO:0140664 Molecular Function | ATP-dependent DNA damage sensor activity | 181 / 228 | 79.4% | 93.3% of 194 | ≥50% support |
| KEGG | K10870 | RAD51L2, RAD51C — DNA repair and recombination proteins | 139 / 228 | 61.0% | 98.6% of 141 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0038.g58.t1 | XP_029184621.2 | DNA repair protein RAD51 homolog 3-like isoform X1 [Acropora millepora] | Q8R2J9 DNA repair protein RAD51 homolog 3 OS=Cricetulus griseus OX= | JBrowse |
