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This orthogroup contains 222 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 222 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14218 | PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2 | 197 / 222 | 88.7% | 100.0% of 197 | ≥80% support |
| Pfam | PF09286 | Pro-kuma_activ — Pro-kumamolisin, activation domain | 192 / 222 | 86.5% | 99.0% of 194 | ≥80% support |
| GO | GO:0004175 Molecular Function | endopeptidase activity | 197 / 222 | 88.7% | 100.0% of 197 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 197 / 222 | 88.7% | 100.0% of 197 | ≥80% support |
| GO | GO:0007417 Biological Process | central nervous system development | 197 / 222 | 88.7% | 100.0% of 197 | ≥80% support |
| GO | GO:0008240 Molecular Function | tripeptidyl-peptidase activity | 197 / 222 | 88.7% | 100.0% of 197 | ≥80% support |
| GO | GO:0008236 Molecular Function | serine-type peptidase activity | 194 / 222 | 87.4% | 98.5% of 197 | ≥80% support |
| GO | GO:0004252 Molecular Function | serine-type endopeptidase activity | 191 / 222 | 86.0% | 97.0% of 197 | ≥80% support |
| KEGG | K01279 | TPP1, CLN2 — Exosome | 186 / 222 | 83.8% | 99.5% of 187 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0301.g15.t1 | XP_029204919.2 | tripeptidyl-peptidase 1-like [Acropora millepora] | O89023 Tripeptidyl-peptidase 1 OS=Mus musculus OX=10090 GN=Tpp1 PE= | JBrowse |
