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This orthogroup contains 194 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 194 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR16821 | FRATAXIN | 168 / 194 | 86.6% | 100.0% of 168 | ≥80% support |
| Pfam | PF01491 | Frataxin_Cyay — Frataxin-like domain | 171 / 194 | 88.1% | 100.0% of 171 | ≥80% support |
| GO | GO:0008199 Molecular Function | ferric iron binding | 172 / 194 | 88.7% | 100.0% of 172 | ≥80% support |
| GO | GO:0016226 Biological Process | iron-sulfur cluster assembly | 172 / 194 | 88.7% | 100.0% of 172 | ≥80% support |
| GO | GO:0004322 Molecular Function | ferroxidase activity | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0006879 Biological Process | intracellular iron ion homeostasis | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0008198 Molecular Function | ferrous iron binding | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0018283 Biological Process | iron incorporation into metallo-sulfur cluster | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0034986 Molecular Function | iron chaperone activity | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| GO | GO:0051537 Molecular Function | 2 iron, 2 sulfur cluster binding | 168 / 194 | 86.6% | 97.7% of 172 | ≥80% support |
| KEGG | K19054 | FXN — Mitochondrial biogenesis | 147 / 194 | 75.8% | 100.0% of 147 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0139.g47.t1 | XP_029186388.2 | LOW QUALITY PROTEIN: frataxin, mitochondrial-like [Acropora millepora] | O35943 Frataxin, mitochondrial OS=Mus musculus OX=10090 GN=Fxn PE=1 | JBrowse |
