← Back to the gene family browser
This orthogroup contains 1,660 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,660 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00229 | TNF | 1371 / 1,660 | 82.6% | 99.6% of 1,377 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 1424 / 1,660 | 85.8% | 99.9% of 1,425 | ≥80% support |
| GO | GO:0005164 Molecular Function | tumor necrosis factor receptor binding | 1387 / 1,660 | 83.6% | 97.3% of 1,425 | ≥80% support |
| GO | GO:0006955 Biological Process | immune response | 1387 / 1,660 | 83.6% | 97.3% of 1,425 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 1387 / 1,660 | 83.6% | 97.3% of 1,425 | ≥80% support |
| PANTHER | PTHR11471 | TUMOR NECROSIS FACTOR FAMILY MEMBER | 1174 / 1,660 | 70.7% | 90.0% of 1,304 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
