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🧬 OG0004832

This orthogroup contains 249 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 88.4%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 249 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR15749FANCONI-ASSOCIATED NUCLEASE 1220 / 24988.4%99.6%
of 221		≥80% support
GOGO:0004518
Molecular Function		nuclease activity220 / 24988.4%99.6%
of 221		≥80% support
GOGO:0036297
Biological Process		interstrand cross-link repair220 / 24988.4%99.6%
of 221		≥80% support
GOGO:0005634
Cellular Component		nucleus217 / 24987.2%98.2%
of 221		≥80% support
GOGO:0008409
Molecular Function		5'-3' exonuclease activity217 / 24987.2%98.2%
of 221		≥80% support
GOGO:0017108
Molecular Function		5'-flap endonuclease activity217 / 24987.2%98.2%
of 221		≥80% support
GOGO:0070336
Molecular Function		flap-structured DNA binding217 / 24987.2%98.2%
of 221		≥80% support
PfamPF21170FAN1_TPR — Fanconi-associated nuclease 1, TPR domain177 / 24971.1%82.7%
of 214		≥50% support
PfamPF08774VRR_NUC — VRR-NUC domain170 / 24968.3%79.4%
of 214		≥50% support
PfamPF21315FAN1_HTH — FAN1, HTH domain166 / 24966.7%77.6%
of 214		≥50% support
GOGO:0016788
Molecular Function		hydrolase activity, acting on ester bonds170 / 24968.3%76.9%
of 221		≥50% support
GOGO:0003676
Molecular Function		nucleic acid binding159 / 24963.9%72.0%
of 221		≥50% support
KEGGK15363FAN1, MTMR15 — DNA repair and recombination proteins134 / 24953.8%97.8%
of 137		≥50% support
📊 Total members in OG0004832: 2 (filtered to AMYRI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)		 Top NCBI-NR hit description
(source organism)		 Top UniProt hit
(Swiss-Prot)		 Genome browser
Astreopora myriophthalmaBRAKERYMEP00000011105.1XP_029185995.2fanconi-associated nuclease 1-like isoform X1 [Acropora millepora]Q1LWH4
Fanconi-associated nuclease 1 OS=Danio rerio OX=7955 GN=fan1		JBrowse
Astreopora myriophthalmag3592.t1.1none–JBrowse
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