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This orthogroup contains 234 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 234 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR22957 | TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN | 192 / 234 | 82.1% | 99.5% of 193 | ≥80% support |
| GO | GO:0005096 Molecular Function | GTPase activator activity | 192 / 234 | 82.1% | 99.5% of 193 | ≥80% support |
| GO | GO:0090630 Biological Process | activation of GTPase activity | 192 / 234 | 82.1% | 99.5% of 193 | ≥80% support |
| GO | GO:0005769 Cellular Component | early endosome | 190 / 234 | 81.2% | 98.5% of 193 | ≥80% support |
| Pfam | PF00566 | RabGAP-TBC — Rab-GTPase-TBC domain | 183 / 234 | 78.2% | 93.9% of 195 | ≥50% support |
| Pfam | PF12068 | PH_RBD — Rab-binding domain (RBD) | 127 / 234 | 54.3% | 65.1% of 195 | ≥50% support |
| KEGG | K24797 | TBC1D16 — Membrane trafficking | 126 / 234 | 53.9% | 95.5% of 132 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astreopora myriophthalma | BRAKERYMEP00000034814.1 | XP_015752147.1 | PREDICTED: TBC1 domain family member 16-like [Acropora digitifera] | – | JBrowse |
| Astreopora myriophthalma | BRAKERYMEP00000034843.1 | XP_029209781.2 | TBC1 domain family member 16-like [Acropora millepora] | Q8TBP0 TBC1 domain family member 16 OS=Homo sapiens OX=9606 GN=TBC1 | JBrowse |
| Astreopora myriophthalma | g7708.t1.1 | none | – | JBrowse | |
| Astreopora myriophthalma | g7709.t1.1 | none | – | JBrowse |
