Gene Family

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Member genes
228
Species
136
Sequences
228
Best annotation support
86.4%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 86.4% of the 228 members.

Support counts the member genes carrying the term. % of genes is that count over all 228 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR21092NICASTRIN197 / 22886.4%99.5%
of 198
≥80% support
PfamPF05450Nicastrin187 / 22882.0%94.9%
of 197
≥80% support
GOGO:0005887
Cellular Component
plasma membrane197 / 22886.4%99.5%
of 198
≥80% support
GOGO:0016020
Cellular Component
membrane197 / 22886.4%99.5%
of 198
≥80% support
GOGO:0016485
Biological Process
protein processing197 / 22886.4%99.5%
of 198
≥80% support
PfamPF18266Ncstrn_small — Nicastrin small lobe181 / 22879.4%91.9%
of 197
≥50% support
KEGGK06171NCSTN — Alzheimer disease160 / 22870.2%99.4%
of 161
≥50% support
📊 Total members in OG0005828: 2 (filtered to AMYRI · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Astreopora myriophthalmaBRAKERYMEP00000004831.1XP_044180244.1nicastrin-like isoform X2 [Acropora millepora]Q92542
Nicastrin OS=Homo sapiens OX=9606 GN=NCSTN PE=1 SV=2
JBrowse
Astreopora myriophthalmag25419.t1.1noneJBrowse
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