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This orthogroup contains 226 genes from 133 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 226 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13622 | THIAMIN PYROPHOSPHOKINASE | 198 / 226 | 87.6% | 99.5% of 199 | ≥80% support |
| Pfam | PF04265 | TPK_B1_binding — Thiamin pyrophosphokinase, vitamin B1 binding domain | 191 / 226 | 84.5% | 95.0% of 201 | ≥80% support |
| Pfam | PF04263 | TPK_catalytic — Thiamin pyrophosphokinase, catalytic domain | 188 / 226 | 83.2% | 93.5% of 201 | ≥80% support |
| GO | GO:0009229 Biological Process | thiamine diphosphate biosynthetic process | 205 / 226 | 90.7% | 100.0% of 205 | ≥80% support |
| GO | GO:0004788 Molecular Function | thiamine diphosphokinase activity | 202 / 226 | 89.4% | 98.5% of 205 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 202 / 226 | 89.4% | 98.5% of 205 | ≥80% support |
| GO | GO:0006772 Biological Process | thiamine metabolic process | 192 / 226 | 85.0% | 93.7% of 205 | ≥80% support |
| GO | GO:0030975 Molecular Function | thiamine binding | 192 / 226 | 85.0% | 93.7% of 205 | ≥80% support |
| KEGG | K00949 | thiN, TPK1, THI80 — Thiamine metabolism | 166 / 226 | 73.5% | 100.0% of 166 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Astreopora myriophthalma | BRAKERYMEP00000027848.1 | XP_029207955.2 | thiamin pyrophosphokinase 1-like isoform X1 [Acropora millepora] | Q9R0M5 Thiamine pyrophosphokinase 1 OS=Mus musculus OX=10090 GN=Tpk | JBrowse |
| Astreopora myriophthalma | g19816.t1.1 | none | – | JBrowse |
