Gene Family

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🧬 OG0000157

This orthogroup contains 3,218 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 75.8%
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Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 3,218 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR11920GUANYLYL CYCLASE2438 / 3,21875.8%85.7%
of 2,846
≥50% support
PfamPF00211Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain2256 / 3,21870.1%78.1%
of 2,888
≥50% support
PfamPF01094ANF_receptor — Receptor family ligand binding region2207 / 3,21868.6%76.4%
of 2,888
≥50% support
PfamPF07714PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase2123 / 3,21866.0%73.5%
of 2,888
≥50% support
GOGO:0004383
Molecular Function
guanylate cyclase activity2439 / 3,21875.8%85.9%
of 2,838
≥50% support
GOGO:0005886
Cellular Component
plasma membrane2439 / 3,21875.8%85.9%
of 2,838
≥50% support
GOGO:0001653
Molecular Function
peptide receptor activity2437 / 3,21875.7%85.9%
of 2,838
≥50% support
GOGO:0004016
Molecular Function
adenylate cyclase activity2437 / 3,21875.7%85.9%
of 2,838
≥50% support
GOGO:0006182
Biological Process
cGMP biosynthetic process2437 / 3,21875.7%85.9%
of 2,838
≥50% support
GOGO:0007168
Biological Process
receptor guanylyl cyclase signaling pathway2437 / 3,21875.7%85.9%
of 2,838
≥50% support
GOGO:0009190
Biological Process
cyclic nucleotide biosynthetic process2259 / 3,21870.2%79.6%
of 2,838
≥50% support
GOGO:0035556
Biological Process
intracellular signal transduction2259 / 3,21870.2%79.6%
of 2,838
≥50% support
GOGO:0004672
Molecular Function
protein kinase activity2162 / 3,21867.2%76.2%
of 2,838
≥50% support
GOGO:0006468
Biological Process
protein phosphorylation2162 / 3,21867.2%76.2%
of 2,838
≥50% support
GOGO:0005524
Molecular Function
ATP binding2127 / 3,21866.1%75.0%
of 2,838
≥50% support
GOGO:0016849
Molecular Function
phosphorus-oxygen lyase activity1828 / 3,21856.8%64.4%
of 2,838
≥50% support
📊 Total members in OG0000157: 13 (filtered to APULC · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Acropora pulchraFUN_016617-T1XP_029213616.2atrial natriuretic peptide receptor 1-like [Acropora millepora]P18293
Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100
JBrowse
Acropora pulchraFUN_016618-T1XP_029213616.2atrial natriuretic peptide receptor 1-like [Acropora millepora]P46197
Atrial natriuretic peptide receptor 2 OS=Bos taurus OX=9913
JBrowse
Acropora pulchraFUN_036983-T1XP_044174474.1atrial natriuretic peptide receptor 1-like [Acropora millepora]P18293
Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100
JBrowse
Acropora pulchraFUN_036983-T2XP_044174474.1atrial natriuretic peptide receptor 1-like [Acropora millepora]P18293
Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100
JBrowse
Acropora pulchraFUN_038383-T1XP_029193317.2atrial natriuretic peptide receptor 2-like isoform X1 [Acropora millepora]P16065
Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE
JBrowse
Acropora pulchraFUN_038383-T2XP_029193317.2atrial natriuretic peptide receptor 2-like isoform X1 [Acropora millepora]P16065
Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE
JBrowse
Acropora pulchraFUN_038385-T1XP_044184619.1speract receptor-like [Acropora millepora]P16065
Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE
JBrowse
Acropora pulchraFUN_038386-T1XP_044184622.1atrial natriuretic peptide receptor 1-like [Acropora millepora]P16065
Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE
JBrowse
Acropora pulchraFUN_038387-T1XP_015762336.1PREDICTED: guanylate cyclase 32E-like [Acropora digitifera]P55202
Atrial natriuretic peptide receptor 2 OS=Anguilla japonica O
JBrowse
Acropora pulchraFUN_038389-T1QCF40880.1receptor guanylate cyclase 3 [Fimbriaphyllia ancora]P16066
Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960
JBrowse
Acropora pulchraFUN_038390-T1QCF40880.1receptor guanylate cyclase 3 [Fimbriaphyllia ancora]P55202
Atrial natriuretic peptide receptor 2 OS=Anguilla japonica O
JBrowse
Acropora pulchraFUN_038391-T1XP_015762337.1PREDICTED: speract receptor-like [Acropora digitifera]Q7JQ32
Receptor-type guanylate cyclase Gyc76C OS=Drosophila melanog
JBrowse
Acropora pulchraFUN_038392-T1QCF40881.1receptor guanylate cyclase 4 [Fimbriaphyllia ancora]P16065
Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE
JBrowse
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