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This orthogroup contains 706 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 706 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR34339 | STIMULATOR OF INTERFERON GENES PROTEIN | 617 / 706 | 87.4% | 99.8% of 618 | ≥80% support |
| Pfam | PF15009 | TMEM173 — Transmembrane protein 173 | 633 / 706 | 89.7% | 99.8% of 634 | ≥80% support |
| GO | GO:0002218 Biological Process | activation of innate immune response | 634 / 706 | 89.8% | 100.0% of 634 | ≥80% support |
| GO | GO:0032481 Biological Process | positive regulation of type I interferon production | 634 / 706 | 89.8% | 100.0% of 634 | ≥80% support |
| GO | GO:0000045 Biological Process | autophagosome assembly | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0005776 Cellular Component | autophagosome | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0005789 Cellular Component | endoplasmic reticulum membrane | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0016239 Biological Process | positive regulation of macroautophagy | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0035438 Molecular Function | cyclic-di-GMP binding | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0045087 Biological Process | innate immune response | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0061507 Molecular Function | 2',3'-cyclic GMP-AMP binding | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| GO | GO:0061709 Biological Process | reticulophagy | 617 / 706 | 87.4% | 97.3% of 634 | ≥80% support |
| KEGG | K12654 | STING1, TMEM173, MITA — Membrane trafficking | 447 / 706 | 63.3% | 99.6% of 449 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_023277-T1 | XP_029195486.2 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023278-T1 | XP_044173241.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023281-T1 | XP_044173241.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023285-T1 | XP_044173242.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023292-T1 | XP_044173241.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023294-T1 | XP_029210561.2 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SES9 Stimulator of interferon genes protein 3 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023295-T1 | XP_044173243.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |
| Acropora pulchra | FUN_023296-T1 | XP_044173243.1 | stimulator of interferon genes protein-like [Acropora millepora] | A0A2B4SJA1 Stimulator of interferon genes protein 2 OS=Stylophora pisti | JBrowse |