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This orthogroup contains 536 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 536 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11977 | VILLIN | 472 / 536 | 88.1% | 100.0% of 472 | ≥80% support |
| Pfam | PF00626 | Gelsolin | 463 / 536 | 86.4% | 97.9% of 473 | ≥80% support |
| GO | GO:0051015 Molecular Function | actin filament binding | 472 / 536 | 88.1% | 99.2% of 476 | ≥80% support |
| GO | GO:0005546 Molecular Function | phosphatidylinositol-4,5-bisphosphate binding | 463 / 536 | 86.4% | 97.3% of 476 | ≥80% support |
| GO | GO:0051014 Biological Process | actin filament severing | 463 / 536 | 86.4% | 97.3% of 476 | ≥80% support |
| GO | GO:0051016 Biological Process | barbed-end actin filament capping | 463 / 536 | 86.4% | 97.3% of 476 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 454 / 536 | 84.7% | 95.4% of 476 | ≥80% support |
| GO | GO:0008154 Biological Process | actin polymerization or depolymerization | 454 / 536 | 84.7% | 95.4% of 476 | ≥80% support |
| GO | GO:0015629 Cellular Component | actin cytoskeleton | 454 / 536 | 84.7% | 95.4% of 476 | ≥80% support |
| Pfam | PF02209 | VHP — Villin headpiece domain | 354 / 536 | 66.0% | 74.8% of 473 | ≥50% support |
| GO | GO:0003779 Molecular Function | actin binding | 359 / 536 | 67.0% | 75.4% of 476 | ≥50% support |
| GO | GO:0007010 Biological Process | cytoskeleton organization | 359 / 536 | 67.0% | 75.4% of 476 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_006820-T1 | XP_029179668.2 | advillin-like isoform X1 [Acropora millepora] | Q9WU06 Advillin OS=Rattus norvegicus OX=10116 GN=Avil PE=2 SV=2 | JBrowse |
| Acropora pulchra | FUN_018023-T1 | XP_044165079.1 | advillin-like [Acropora millepora] | Q9WU06 Advillin OS=Rattus norvegicus OX=10116 GN=Avil PE=2 SV=2 | JBrowse |
