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This orthogroup contains 519 genes from 138 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 519 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12157 | REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| Pfam | PF00168 | C2 | 434 / 519 | 83.6% | 93.9% of 462 | ≥80% support |
| GO | GO:0006887 Biological Process | exocytosis | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| GO | GO:0031267 Molecular Function | small GTPase binding | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| GO | GO:0044325 Molecular Function | transmembrane transporter binding | 474 / 519 | 91.3% | 100.0% of 474 | ≥80% support |
| GO | GO:0042734 Cellular Component | presynaptic membrane | 457 / 519 | 88.1% | 96.4% of 474 | ≥80% support |
| GO | GO:0048167 Biological Process | regulation of synaptic plasticity | 457 / 519 | 88.1% | 96.4% of 474 | ≥80% support |
| GO | GO:0048788 Cellular Component | cytoskeleton of presynaptic active zone | 457 / 519 | 88.1% | 96.4% of 474 | ≥80% support |
| GO | GO:0048791 Biological Process | calcium ion-regulated exocytosis of neurotransmitter | 457 / 519 | 88.1% | 96.4% of 474 | ≥80% support |
| GO | GO:0050806 Biological Process | positive regulation of synaptic transmission | 457 / 519 | 88.1% | 96.4% of 474 | ≥80% support |
| Pfam | PF00595 | PDZ | 359 / 519 | 69.2% | 77.7% of 462 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 373 / 519 | 71.9% | 78.7% of 474 | ≥50% support |
| GO | GO:0006886 Biological Process | intracellular protein transport | 286 / 519 | 55.1% | 60.3% of 474 | ≥50% support |
| KEGG | K15297 | RIMS2, RIM2 — Membrane trafficking | 299 / 519 | 57.6% | 95.8% of 312 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_008909-T1 | XP_044180837.1 | regulating synaptic membrane exocytosis protein 2-like isoform X7 [Acropora millepora] | Q9EQZ7 Regulating synaptic membrane exocytosis protein 2 OS=Mus mus | JBrowse |
