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This orthogroup contains 309 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 309 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR45865 | E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER | 262 / 309 | 84.8% | 99.2% of 264 | ≥80% support |
| GO | GO:0000209 Biological Process | protein polyubiquitination | 262 / 309 | 84.8% | 99.2% of 264 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 262 / 309 | 84.8% | 99.2% of 264 | ≥80% support |
| GO | GO:0006974 Biological Process | DNA damage response | 262 / 309 | 84.8% | 99.2% of 264 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 262 / 309 | 84.8% | 99.2% of 264 | ≥80% support |
| Pfam | PF00176 | SNF2-rel_dom — SNF2-related domain | 213 / 309 | 68.9% | 81.9% of 260 | ≥50% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 198 / 309 | 64.1% | 76.2% of 260 | ≥50% support |
| Pfam | PF21325 | SHPRH_helical-1st — E3 ubiquitin-protein ligase SHPRH, first helical domain | 192 / 309 | 62.1% | 73.9% of 260 | ≥50% support |
| Pfam | PF21324 | SHPRH_helical-2nd — E3 ubiquitin-protein ligase SHPRH, second helical domain | 169 / 309 | 54.7% | 65.0% of 260 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 215 / 309 | 69.6% | 81.4% of 264 | ≥50% support |
| GO | GO:0140658 Molecular Function | ATP-dependent chromatin remodeler activity | 213 / 309 | 68.9% | 80.7% of 264 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_008955-T1 | XP_029195674.2 | E3 ubiquitin-protein ligase SHPRH-like [Acropora millepora] | Q149N8 E3 ubiquitin-protein ligase SHPRH OS=Homo sapiens OX=9606 GN | JBrowse |
