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This orthogroup contains 303 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 303 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| GO | GO:0006468 Biological Process | protein phosphorylation | 248 / 303 | 81.9% | 94.7% of 262 | ≥80% support |
| GO | GO:0004713 Molecular Function | protein tyrosine kinase activity | 247 / 303 | 81.5% | 94.3% of 262 | ≥80% support |
| PANTHER | PTHR46221 | FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER | 239 / 303 | 78.9% | 94.5% of 253 | ≥50% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 226 / 303 | 74.6% | 85.9% of 263 | ≥50% support |
| Pfam | PF03623 | Focal_AT — Focal adhesion targeting region | 222 / 303 | 73.3% | 84.4% of 263 | ≥50% support |
| Pfam | PF21477 | FERM_C_FAK1 — FAK1/PYK2, FERM domain C-lobe | 210 / 303 | 69.3% | 79.9% of 263 | ≥50% support |
| Pfam | PF00373 | FERM_M — FERM central domain | 195 / 303 | 64.4% | 74.1% of 263 | ≥50% support |
| Pfam | PF18038 | FERM_N_2 — FERM N-terminal domain | 193 / 303 | 63.7% | 73.4% of 263 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 226 / 303 | 74.6% | 86.3% of 262 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 224 / 303 | 73.9% | 85.5% of 262 | ≥50% support |
| GO | GO:0005925 Cellular Component | focal adhesion | 224 / 303 | 73.9% | 85.5% of 262 | ≥50% support |
| GO | GO:0007172 Biological Process | signal complex assembly | 223 / 303 | 73.6% | 85.1% of 262 | ≥50% support |
| GO | GO:0005856 Cellular Component | cytoskeleton | 206 / 303 | 68.0% | 78.6% of 262 | ≥50% support |
| KEGG | K05725 | PTK2, FAK — Protein phosphatases and associated proteins | 194 / 303 | 64.0% | 97.0% of 200 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_015998-T1 | XP_029191417.2 | focal adhesion kinase 1-like isoform X2 [Acropora millepora] | Q00944 Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE= | JBrowse |