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This orthogroup contains 251 genes from 140 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 251 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18968 | THIAMINE PYROPHOSPHATE ENZYMES | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0003984 Molecular Function | acetolactate synthase activity | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0005948 Cellular Component | acetolactate synthase complex | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0009097 Biological Process | isoleucine biosynthetic process | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0009099 Biological Process | L-valine biosynthetic process | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0030976 Molecular Function | thiamine pyrophosphate binding | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0050660 Molecular Function | flavin adenine dinucleotide binding | 221 / 251 | 88.1% | 99.1% of 223 | ≥80% support |
| GO | GO:0000287 Molecular Function | magnesium ion binding | 206 / 251 | 82.1% | 92.4% of 223 | ≥80% support |
| Pfam | PF02775 | TPP_enzyme_C — Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | 197 / 251 | 78.5% | 88.7% of 222 | ≥50% support |
| Pfam | PF02776 | TPP_enzyme_N — Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | 190 / 251 | 75.7% | 85.6% of 222 | ≥50% support |
| Pfam | PF00205 | TPP_enzyme_M — Thiamine pyrophosphate enzyme, central domain | 187 / 251 | 74.5% | 84.2% of 222 | ≥50% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 197 / 251 | 78.5% | 88.3% of 223 | ≥50% support |
| KEGG | K11259 | ILVBL, HACL2 — Enzymes with EC numbers | 176 / 251 | 70.1% | 97.2% of 181 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_036921-T1 | XP_044174531.1 | 2-hydroxyacyl-CoA lyase 2-like [Acropora millepora] | Q6NV04 2-hydroxyacyl-CoA lyase 2 OS=Danio rerio OX=7955 GN=ilvbl PE | JBrowse |
