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This orthogroup contains 248 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 248 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23382 | MALATE DEHYDROGENASE | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| Pfam | PF00056 | Ldh_1_N — lactate/malate dehydrogenase, NAD binding domain | 216 / 248 | 87.1% | 96.9% of 223 | ≥80% support |
| Pfam | PF02866 | Ldh_1_C — lactate/malate dehydrogenase, alpha/beta C-terminal domain | 215 / 248 | 86.7% | 96.4% of 223 | ≥80% support |
| GO | GO:0006099 Biological Process | tricarboxylic acid cycle | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0006107 Biological Process | oxaloacetate metabolic process | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0006108 Biological Process | malate metabolic process | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0006734 Biological Process | NADH metabolic process | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0016615 Molecular Function | malate dehydrogenase activity | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0030060 Molecular Function | L-malate dehydrogenase (NAD+) activity | 223 / 248 | 89.9% | 100.0% of 223 | ≥80% support |
| GO | GO:0003824 Molecular Function | catalytic activity | 216 / 248 | 87.1% | 96.9% of 223 | ≥80% support |
| GO | GO:0016491 Molecular Function | oxidoreductase activity | 216 / 248 | 87.1% | 96.9% of 223 | ≥80% support |
| GO | GO:0016616 Molecular Function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 216 / 248 | 87.1% | 96.9% of 223 | ≥80% support |
| GO | GO:0019752 Biological Process | carboxylic acid metabolic process | 188 / 248 | 75.8% | 84.3% of 223 | ≥50% support |
| GO | GO:0005739 Cellular Component | mitochondrion | 152 / 248 | 61.3% | 68.2% of 223 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 152 / 248 | 61.3% | 68.2% of 223 | ≥50% support |
| KEGG | K00025 | MDH1 — Proximal tubule bicarbonate reclamation | 186 / 248 | 75.0% | 93.5% of 199 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_032004-T1 | XP_029189259.2 | malate dehydrogenase, cytoplasmic-like [Acropora millepora] | Q5ZME2 Malate dehydrogenase, cytoplasmic OS=Gallus gallus OX=9031 G | JBrowse |
