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This orthogroup contains 247 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 247 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13759 | TWINFILIN | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| Pfam | PF00241 | Cofilin_ADF — Cofilin/tropomyosin-type actin-binding protein | 204 / 247 | 82.6% | 99.5% of 205 | ≥80% support |
| GO | GO:0003779 Molecular Function | actin binding | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0003785 Molecular Function | actin monomer binding | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0005884 Cellular Component | actin filament | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0030042 Biological Process | actin filament depolymerization | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0030837 Biological Process | negative regulation of actin filament polymerization | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0042989 Biological Process | sequestering of actin monomers | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0051015 Molecular Function | actin filament binding | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0051016 Biological Process | barbed-end actin filament capping | 211 / 247 | 85.4% | 99.5% of 212 | ≥80% support |
| GO | GO:0010591 Biological Process | regulation of lamellipodium assembly | 207 / 247 | 83.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0010976 Biological Process | positive regulation of neuron projection development | 207 / 247 | 83.8% | 97.6% of 212 | ≥80% support |
| GO | GO:0030016 Cellular Component | myofibril | 207 / 247 | 83.8% | 97.6% of 212 | ≥80% support |
| KEGG | K08870 | TWF — Cilium and associated proteins | 169 / 247 | 68.4% | 98.8% of 171 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_008751-T1 | XP_029185555.1 | twinfilin-1-like [Acropora millepora] | Q5I082 Twinfilin-1 OS=Xenopus tropicalis OX=8364 GN=twf1 PE=2 SV=1 | JBrowse |
