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This orthogroup contains 234 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 234 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR20338 | NUCLEAR RESPIRATORY FACTOR 1 | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| Pfam | PF10491 | Nrf1_DNA-bind — NLS-binding and DNA-binding and dimerisation domains of Nrf1 | 204 / 234 | 87.2% | 100.0% of 204 | ≥80% support |
| GO | GO:0000978 Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| GO | GO:0000981 Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| GO | GO:0003700 Molecular Function | DNA-binding transcription factor activity | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| GO | GO:0006357 Biological Process | regulation of transcription by RNA polymerase II | 201 / 234 | 85.9% | 100.0% of 201 | ≥80% support |
| KEGG | K11831 | NRF1 — Mitochondrial biogenesis | 192 / 234 | 82.1% | 99.5% of 193 | ≥80% support |
| Pfam | PF10492 | Nrf1_activ_bdg — Nrf1 activator activation site binding domain | 154 / 234 | 65.8% | 75.5% of 204 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_002722-T1 | XP_015776740.1 | PREDICTED: nuclear respiratory factor 1-like [Acropora digitifera] | Q16656 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 | JBrowse |
