Gene Family

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🧬 OG0005866

This orthogroup contains 227 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 82.8%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 227 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10865METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0000122
Biological Process
negative regulation of transcription by RNA polymerase II188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0003713
Molecular Function
transcription coactivator activity188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0003714
Molecular Function
transcription corepressor activity188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0005654
Cellular Component
nucleoplasm188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0016575
Biological Process
obsolete histone deacetylation188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0016581
Cellular Component
NuRD complex188 / 22782.8%99.0%
of 190
≥80% support
GOGO:0042826
Molecular Function
histone deacetylase binding188 / 22782.8%99.0%
of 190
≥80% support
PfamPF17226MTA_R1 — MTA R1 domain175 / 22777.1%94.1%
of 186
≥50% support
PfamPF01448ELM2173 / 22776.2%93.0%
of 186
≥50% support
PfamPF01426BAH168 / 22774.0%90.3%
of 186
≥50% support
PfamPF00096zf-C2H2 — Zinc finger, C2H2 type161 / 22770.9%86.6%
of 186
≥50% support
PfamPF00249Myb_DNA-binding — Myb-like DNA-binding domain129 / 22756.8%69.4%
of 186
≥50% support
GOGO:0003682
Molecular Function
chromatin binding171 / 22775.3%90.0%
of 190
≥50% support
GOGO:0043565
Molecular Function
sequence-specific DNA binding167 / 22773.6%87.9%
of 190
≥50% support
GOGO:0006355
Biological Process
regulation of DNA-templated transcription167 / 22773.6%87.9%
of 190
≥50% support
KEGGK11660MTA — Chromosome and associated proteins167 / 22773.6%97.7%
of 171
≥50% support
📊 Total members in OG0005866: 1 (filtered to APULC · show all species)
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Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Acropora pulchraFUN_032123-T1XP_029201970.2metastasis-associated protein MTA3-like [Acropora millepora]Q8K4B0
Metastasis-associated protein MTA1 OS=Mus musculus OX=10090
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