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This orthogroup contains 226 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 226 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10603 | FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| Pfam | PF17904 | KH_9 — FMRP KH0 domain | 184 / 226 | 81.4% | 96.8% of 190 | ≥80% support |
| Pfam | PF00013 | KH_1 — KH domain | 184 / 226 | 81.4% | 96.8% of 190 | ≥80% support |
| GO | GO:0005634 Cellular Component | nucleus | 191 / 226 | 84.5% | 100.0% of 191 | ≥80% support |
| GO | GO:0003729 Molecular Function | mRNA binding | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0003730 Molecular Function | mRNA 3'-UTR binding | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0005844 Cellular Component | obsolete polysome | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0006417 Biological Process | regulation of translation | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0017148 Biological Process | negative regulation of translation | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0036464 Cellular Component | cytoplasmic ribonucleoprotein granule | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0042803 Molecular Function | protein homodimerization activity | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0043488 Biological Process | regulation of mRNA stability | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0045182 Molecular Function | translation regulator activity | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0045727 Biological Process | positive regulation of translation | 190 / 226 | 84.1% | 99.5% of 191 | ≥80% support |
| GO | GO:0003723 Molecular Function | RNA binding | 188 / 226 | 83.2% | 98.4% of 191 | ≥80% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 182 / 226 | 80.5% | 95.3% of 191 | ≥80% support |
| Pfam | PF05641 | Agenet | 152 / 226 | 67.3% | 80.0% of 190 | ≥50% support |
| Pfam | PF18336 | Tudor_FRX1 — Fragile X messenger ribonucleoprotein 1, Tudor domain | 152 / 226 | 67.3% | 80.0% of 190 | ≥50% support |
| KEGG | K15516 | FMR — Messenger RNA biogenesis | 167 / 226 | 73.9% | 98.2% of 170 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_028511-T1 | XP_015761948.1 | PREDICTED: fragile X mental retardation protein 1 homolog A-like isoform X1 [Acropora digitifera] | P51113 Fragile X messenger ribonucleoprotein 1 homolog A OS=Xenopus | JBrowse |
