← Back to the gene family browser
This orthogroup contains 207 genes from 129 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 207 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00619 | CARD — Caspase recruitment domain | 172 / 207 | 83.1% | 100.0% of 172 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 174 / 207 | 84.1% | 100.0% of 174 | ≥80% support |
| PANTHER | PTHR34920 | B-CELL LYMPHOMA/LEUKEMIA 10 | 133 / 207 | 64.3% | 79.6% of 167 | ≥50% support |
| GO | GO:0002250 Biological Process | adaptive immune response | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0003713 Molecular Function | transcription coactivator activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0005829 Cellular Component | cytosol | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0006915 Biological Process | apoptotic process | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0007249 Biological Process | canonical NF-kappaB signal transduction | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0019209 Molecular Function | kinase activator activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0032449 Cellular Component | CBM complex | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0043422 Molecular Function | protein kinase B binding | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0051059 Molecular Function | NF-kappaB binding | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:0051092 Biological Process | positive regulation of NF-kappaB transcription factor activity | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
| GO | GO:2001238 Biological Process | positive regulation of extrinsic apoptotic signaling pathway | 133 / 207 | 64.3% | 76.4% of 174 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_025374-T1 | XP_044167656.1 | caspase-2-like [Acropora millepora] | P42575 Caspase-2 OS=Homo sapiens OX=9606 GN=CASP2 PE=1 SV=2 | JBrowse |
| Acropora pulchra | FUN_025376-T1 | XP_044167659.1 | caspase-2-like [Acropora millepora] | P55215 Caspase-2 OS=Rattus norvegicus OX=10116 GN=Casp2 PE=1 SV=3 | JBrowse |
| Acropora pulchra | FUN_025378-T1 | XP_044167656.1 | caspase-2-like [Acropora millepora] | P55215 Caspase-2 OS=Rattus norvegicus OX=10116 GN=Casp2 PE=1 SV=3 | JBrowse |
| Acropora pulchra | FUN_025380-T1 | XP_044167659.1 | caspase-2-like [Acropora millepora] | P42575 Caspase-2 OS=Homo sapiens OX=9606 GN=CASP2 PE=1 SV=2 | JBrowse |
| Acropora pulchra | FUN_025382-T1 | XP_044167657.1 | caspase-2-like [Acropora millepora] | – | JBrowse |
| Acropora pulchra | FUN_043162-T1 | XP_029182738.2 | uncharacterized protein LOC114950765 isoform X1 [Acropora millepora] | – | JBrowse |
