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This orthogroup contains 205 genes from 109 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 205 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR23113 | GUANINE NUCLEOTIDE EXCHANGE FACTOR | 170 / 205 | 82.9% | 99.4% of 171 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 170 / 205 | 82.9% | 98.3% of 173 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 170 / 205 | 82.9% | 98.3% of 173 | ≥80% support |
| GO | GO:0007264 Biological Process | small GTPase-mediated signal transduction | 170 / 205 | 82.9% | 98.3% of 173 | ≥80% support |
| GO | GO:0007265 Biological Process | Ras protein signal transduction | 170 / 205 | 82.9% | 98.3% of 173 | ≥80% support |
| GO | GO:0043547 Biological Process | positive regulation of GTPase activity | 170 / 205 | 82.9% | 98.3% of 173 | ≥80% support |
| Pfam | PF00617 | RasGEF | 162 / 205 | 79.0% | 91.0% of 178 | ≥50% support |
| Pfam | PF00618 | RasGEF_N — RasGEF N-terminal motif | 107 / 205 | 52.2% | 60.1% of 178 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_037321-T1 | XP_029211887.2 | ras-GEF domain-containing family member 1B-like [Acropora millepora] | A4IFE4 Ras-GEF domain-containing family member 1B OS=Bos taurus OX= | JBrowse |
