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This orthogroup contains 199 genes from 78 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 199 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR15706 | SH3 MULTIPLE DOMAIN | 173 / 199 | 86.9% | 99.4% of 174 | ≥80% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 165 / 199 | 82.9% | 95.4% of 173 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 173 / 199 | 86.9% | 94.0% of 184 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 168 / 199 | 84.4% | 91.3% of 184 | ≥80% support |
| GO | GO:0035091 Molecular Function | phosphatidylinositol binding | 168 / 199 | 84.4% | 91.3% of 184 | ≥80% support |
| Pfam | PF07653 | SH3_2 — Variant SH3 domain | 124 / 199 | 62.3% | 71.7% of 173 | ≥50% support |
| Pfam | PF00787 | PX | 122 / 199 | 61.3% | 70.5% of 173 | ≥50% support |
| GO | GO:0016176 Molecular Function | superoxide-generating NADPH oxidase activator activity | 135 / 199 | 67.8% | 73.4% of 184 | ≥50% support |
| GO | GO:0042554 Biological Process | superoxide anion generation | 135 / 199 | 67.8% | 73.4% of 184 | ≥50% support |
| KEGG | K24032 | SH3PXD2 — Membrane trafficking | 104 / 199 | 52.3% | 99.1% of 105 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_023410-T1 | XP_029209046.2 | SH3 and PX domain-containing protein 2B-like [Acropora millepora] | Q1LYG0 SH3 and PX domain-containing protein 2A OS=Danio rerio OX=79 | JBrowse |
