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This orthogroup contains 193 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 193 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11309 | FRIZZLED | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| Pfam | PF01534 | Frizzled | 169 / 193 | 87.6% | 97.7% of 173 | ≥80% support |
| GO | GO:0007417 Biological Process | central nervous system development | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0071679 Biological Process | commissural neuron axon guidance | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0030425 Cellular Component | dendrite | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0016021 Cellular Component | membrane | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0007389 Biological Process | pattern specification process | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0007224 Biological Process | smoothened signaling pathway | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0005929 Cellular Component | cilium | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0005113 Molecular Function | patched binding | 173 / 193 | 89.6% | 100.0% of 173 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 169 / 193 | 87.6% | 97.7% of 173 | ≥80% support |
| GO | GO:0007166 Biological Process | cell surface receptor signaling pathway | 169 / 193 | 87.6% | 97.7% of 173 | ≥80% support |
| Pfam | PF01392 | Fz | 121 / 193 | 62.7% | 69.9% of 173 | ≥50% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 154 / 193 | 79.8% | 89.0% of 173 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 134 / 193 | 69.4% | 77.5% of 173 | ≥50% support |
| KEGG | K06226 | SMO — G protein-coupled receptors | 105 / 193 | 54.4% | 89.0% of 118 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_033022-T1 | XP_029190892.2 | smoothened homolog isoform X1 [Acropora millepora] | Q99835 Protein smoothened OS=Homo sapiens OX=9606 GN=SMO PE=1 SV=1 | JBrowse |
