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This orthogroup contains 188 genes from 136 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 188 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13401 | RAGULATOR COMPLEX PROTEIN LAMTOR1 | 153 / 188 | 81.4% | 99.4% of 154 | ≥80% support |
| GO | GO:0001919 Biological Process | regulation of receptor recycling | 155 / 188 | 82.5% | 100.0% of 155 | ≥80% support |
| GO | GO:0043410 Biological Process | positive regulation of MAPK cascade | 155 / 188 | 82.5% | 100.0% of 155 | ≥80% support |
| GO | GO:0071230 Biological Process | cellular response to amino acid stimulus | 155 / 188 | 82.5% | 100.0% of 155 | ≥80% support |
| GO | GO:0071986 Cellular Component | Ragulator complex | 155 / 188 | 82.5% | 100.0% of 155 | ≥80% support |
| GO | GO:0005085 Molecular Function | guanyl-nucleotide exchange factor activity | 153 / 188 | 81.4% | 98.7% of 155 | ≥80% support |
| GO | GO:0005764 Cellular Component | lysosome | 153 / 188 | 81.4% | 98.7% of 155 | ≥80% support |
| GO | GO:0060090 Molecular Function | molecular adaptor activity | 153 / 188 | 81.4% | 98.7% of 155 | ≥80% support |
| Pfam | PF15454 | LAMTOR — Late endosomal/lysosomal adaptor and MAPK and MTOR activator | 150 / 188 | 79.8% | 99.3% of 151 | ≥50% support |
| GO | GO:0007040 Biological Process | lysosome organization | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| GO | GO:0016197 Biological Process | endosomal transport | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| GO | GO:0031902 Cellular Component | late endosome membrane | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| GO | GO:0032008 Biological Process | positive regulation of TOR signaling | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| GO | GO:0042632 Biological Process | cholesterol homeostasis | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| GO | GO:0045121 Cellular Component | membrane raft | 150 / 188 | 79.8% | 96.8% of 155 | ≥50% support |
| KEGG | K20397 | LAMTOR1 — mTOR signaling pathway | 95 / 188 | 50.5% | 96.9% of 98 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_007176-T1 | XP_015771233.1 | PREDICTED: ragulator complex protein LAMTOR1-like [Acropora digitifera] | Q9CQ22 Ragulator complex protein LAMTOR1 OS=Mus musculus OX=10090 G | JBrowse |
