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This orthogroup contains 172 genes from 132 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 172 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR14879 | CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING | 152 / 172 | 88.4% | 99.4% of 153 | ≥80% support |
| Pfam | PF13920 | zf-C3HC4_3 — Zinc finger, C3HC4 type (RING finger) | 143 / 172 | 83.1% | 98.6% of 145 | ≥80% support |
| GO | GO:0061630 Molecular Function | ubiquitin protein ligase activity | 150 / 172 | 87.2% | 100.0% of 150 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| GO | GO:0043161 Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| GO | GO:0070936 Biological Process | protein K48-linked ubiquitination | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| GO | GO:1902042 Biological Process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| GO | GO:2001271 Biological Process | obsolete negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | 149 / 172 | 86.6% | 99.3% of 150 | ≥80% support |
| KEGG | K20804 | RNF34 — Ubiquitin system | 133 / 172 | 77.3% | 97.8% of 136 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora pulchra | FUN_015053-T1 | XP_015762445.1 | PREDICTED: E3 ubiquitin-protein ligase RNF34-like [Acropora digitifera] | Q5NVC7 E3 ubiquitin-protein ligase RNF34 OS=Pongo abelii OX=9601 GN | JBrowse |
