Gene Family

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Member genes
846
Species
141
Sequences
846
Best annotation support
84.4%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 84.4% of the 846 members.

Support counts the member genes carrying the term. % of genes is that count over all 846 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR22826RHO GUANINE EXCHANGE FACTOR-RELATED714 / 84684.4%94.7%
of 754
≥80% support
GOGO:0005085
Molecular Function
guanyl-nucleotide exchange factor activity718 / 84684.9%94.7%
of 758
≥80% support
GOGO:0005737
Cellular Component
cytoplasm716 / 84684.6%94.5%
of 758
≥80% support
GOGO:0005515
Molecular Function
protein binding695 / 84682.2%91.7%
of 758
≥80% support
PfamPF00621RhoGEF641 / 84675.8%87.8%
of 730
≥50% support
PfamPF00041fn3 — Fibronectin type III domain599 / 84670.8%82.1%
of 730
≥50% support
PfamPF00435Spectrin553 / 84665.4%75.8%
of 730
≥50% support
PfamPF00069Pkinase — Protein kinase domain483 / 84657.1%66.2%
of 730
≥50% support
PfamPF07653SH3_2 — Variant SH3 domain435 / 84651.4%59.6%
of 730
≥50% support
PfamPF07679I-set429 / 84650.7%58.8%
of 730
≥50% support
GOGO:0004672
Molecular Function
protein kinase activity485 / 84657.3%64.0%
of 758
≥50% support
GOGO:0005524
Molecular Function
ATP binding484 / 84657.2%63.9%
of 758
≥50% support
GOGO:0006468
Biological Process
protein phosphorylation484 / 84657.2%63.9%
of 758
≥50% support
📊 Total members in OG0000877: 11 (filtered to AXANT · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Anthopleura xanthogrammicaENSOJPP00000037125.1XP_031555356.1kalirin-like isoform X5 [Actinia tenebrosa]Q8WZ42
Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037146.1XP_031555354.1triple functional domain protein-like isoform X3 [Actinia tenebrosa]O60229
Kalirin OS=Homo sapiens OX=9606 GN=KALRN PE=1 SV=3
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037162.1XP_031555353.1triple functional domain protein-like isoform X2 [Actinia tenebrosa]O60229
Kalirin OS=Homo sapiens OX=9606 GN=KALRN PE=1 SV=3
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037181.1XP_031555357.1triple functional domain protein-like isoform X6 [Actinia tenebrosa]O60229
Kalirin OS=Homo sapiens OX=9606 GN=KALRN PE=1 SV=3
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037202.1XP_031555361.1triple functional domain protein-like isoform X7 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037225.1XP_031555354.1triple functional domain protein-like isoform X3 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037248.1XP_031555356.1kalirin-like isoform X5 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037283.1XP_031555353.1triple functional domain protein-like isoform X2 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037307.1XP_031555351.1triple functional domain protein-like isoform X1 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037332.1XP_031555351.1triple functional domain protein-like isoform X1 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
Anthopleura xanthogrammicaENSOJPP00000037358.1XP_031555354.1triple functional domain protein-like isoform X3 [Actinia tenebrosa]A2CG49
Kalirin OS=Mus musculus OX=10090 GN=Kalrn PE=1 SV=1
JBrowse
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