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This orthogroup contains 310 genes from 137 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 310 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR12560 | LONGEVITY ASSURANCE FACTOR 1 LAG1 | 262 / 310 | 84.5% | 100.0% of 262 | ≥80% support |
| Pfam | PF03798 | TRAM_LAG1_CLN8 — TLC domain | 262 / 310 | 84.5% | 100.0% of 262 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 262 / 310 | 84.5% | 99.6% of 263 | ≥80% support |
| GO | GO:0046513 Biological Process | ceramide biosynthetic process | 262 / 310 | 84.5% | 99.6% of 263 | ≥80% support |
| GO | GO:0050291 Molecular Function | sphingosine N-acyltransferase activity | 262 / 310 | 84.5% | 99.6% of 263 | ≥80% support |
| KEGG | K04710 | CERS1, LASS1 — Sphingolipid signaling pathway | 213 / 310 | 68.7% | 98.6% of 216 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Anthopleura xanthogrammica | ENSOJPP00000004217.1 | XP_031564644.1 | ceramide synthase 1-like [Actinia tenebrosa] | P27544 Ceramide synthase 1 OS=Homo sapiens OX=9606 GN=CERS1 PE=1 SV | JBrowse |
