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Support counts the member genes carrying the term. % of genes is that count over all 293 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13954 | IRE1-RELATED | 235 / 293 | 80.2% | 97.5% of 241 | ≥80% support |
| GO | GO:0004521 Molecular Function | RNA endonuclease activity | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:1990604 Cellular Component | IRE1-TRAF2-ASK1 complex | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:0070059 Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:0051082 Molecular Function | unfolded protein binding | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:0030968 Biological Process | endoplasmic reticulum unfolded protein response | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| GO | GO:0036498 Biological Process | IRE1-mediated unfolded protein response | 235 / 293 | 80.2% | 94.0% of 250 | ≥80% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 228 / 293 | 77.8% | 92.7% of 246 | ≥50% support |
| Pfam | PF06479 | Ribonuc_2-5A — Ribonuclease 2-5A | 206 / 293 | 70.3% | 83.7% of 246 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 230 / 293 | 78.5% | 92.0% of 250 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 230 / 293 | 78.5% | 92.0% of 250 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 230 / 293 | 78.5% | 92.0% of 250 | ≥50% support |
| GO | GO:0004540 Molecular Function | RNA nuclease activity | 207 / 293 | 70.7% | 82.8% of 250 | ≥50% support |
| GO | GO:0006397 Biological Process | mRNA processing | 206 / 293 | 70.3% | 82.4% of 250 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 204 / 293 | 69.6% | 81.6% of 250 | ≥50% support |
| KEGG | K08852 | ERN1 — Protein kinases | 181 / 293 | 61.8% | 96.8% of 187 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Anthopleura xanthogrammica | ENSOJPP00000024990.1 | XP_031563309.1 | serine/threonine-protein kinase/endoribonuclease IRE2-like isoform X1 [Actinia tenebrosa] | O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Hom | JBrowse |
| Anthopleura xanthogrammica | ENSOJPP00000025005.1 | XP_031563309.1 | serine/threonine-protein kinase/endoribonuclease IRE2-like isoform X1 [Actinia tenebrosa] | Q9EQY0 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Mus | JBrowse |
