Gene Family

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Member genes
235
Species
140
Sequences
235
Best annotation support
90.2%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.2% of the 235 members.

Support counts the member genes carrying the term. % of genes is that count over all 235 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR433233-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE212 / 23590.2%100.0%
of 212
≥80% support
PfamPF08540HMG_CoA_synt_C — Hydroxymethylglutaryl-coenzyme A synthase C terminal208 / 23588.5%98.1%
of 212
≥80% support
PfamPF01154HMG_CoA_synt_N — Hydroxymethylglutaryl-coenzyme A synthase N terminal196 / 23583.4%92.5%
of 212
≥80% support
GOGO:0004421
Molecular Function
hydroxymethylglutaryl-CoA synthase activity212 / 23590.2%100.0%
of 212
≥80% support
GOGO:0006084
Biological Process
acetyl-CoA metabolic process212 / 23590.2%100.0%
of 212
≥80% support
GOGO:0010142
Biological Process
farnesyl diphosphate biosynthetic process, mevalonate pathway212 / 23590.2%100.0%
of 212
≥80% support
GOGO:0016746
Molecular Function
acyltransferase activity212 / 23590.2%100.0%
of 212
≥80% support
GOGO:0008299
Biological Process
isoprenoid biosynthetic process193 / 23582.1%91.0%
of 212
≥80% support
KEGGK01641HMGCS — PPAR signaling pathway171 / 23572.8%99.4%
of 172
≥50% support
📊 Total members in OG0005496: 4 (filtered to AXANT · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Anthopleura xanthogrammicaENSOJPP00000011473.1XP_031551578.1hydroxymethylglutaryl-CoA synthase 1-like [Actinia tenebrosa]P23228
Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus ga
JBrowse
Anthopleura xanthogrammicaENSOJPP00000011503.1XP_031551578.1hydroxymethylglutaryl-CoA synthase 1-like [Actinia tenebrosa]P54961
Hydroxymethylglutaryl-CoA synthase 1 OS=Blattella germanica
JBrowse
Anthopleura xanthogrammicaENSOJPP00000011505.1XP_031551578.1hydroxymethylglutaryl-CoA synthase 1-like [Actinia tenebrosa]P23228
Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus ga
JBrowse
Anthopleura xanthogrammicaENSOJPP00000012354.1XP_031551578.1hydroxymethylglutaryl-CoA synthase 1-like [Actinia tenebrosa]O02734
Hydroxymethylglutaryl-CoA synthase, mitochondrial OS=Sus scr
JBrowse
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