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This orthogroup contains 177 genes from 106 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 177 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24416 | TYROSINE-PROTEIN KINASE RECEPTOR | 132 / 177 | 74.6% | 82.0% of 161 | ≥50% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 134 / 177 | 75.7% | 83.8% of 160 | ≥50% support |
| Pfam | PF00431 | CUB | 132 / 177 | 74.6% | 82.5% of 160 | ≥50% support |
| Pfam | PF07679 | I-set | 116 / 177 | 65.5% | 72.5% of 160 | ≥50% support |
| Pfam | PF13927 | Ig_3 — Immunoglobulin domain | 106 / 177 | 59.9% | 66.3% of 160 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 134 / 177 | 75.7% | 93.7% of 143 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 134 / 177 | 75.7% | 93.7% of 143 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 134 / 177 | 75.7% | 93.7% of 143 | ≥50% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 133 / 177 | 75.1% | 93.0% of 143 | ≥50% support |
| GO | GO:0014068 Biological Process | obsolete positive regulation of phosphatidylinositol 3-kinase signaling | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0043235 Cellular Component | receptor complex | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0033674 Biological Process | positive regulation of kinase activity | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0017147 Molecular Function | Wnt-protein binding | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0010976 Biological Process | positive regulation of neuron projection development | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0007169 Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
| GO | GO:0004714 Molecular Function | transmembrane receptor protein tyrosine kinase activity | 132 / 177 | 74.6% | 92.3% of 143 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Anthopleura xanthogrammica | ENSOJPP00000014248.1 | XP_031550525.1 | NT-3 growth factor receptor-like [Actinia tenebrosa] | Q62838 Muscle, skeletal receptor tyrosine protein kinase OS=Rattus | JBrowse |