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This orthogroup contains 316 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 316 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13865 | TIGHT JUNCTION PROTEIN | 272 / 316 | 86.1% | 99.3% of 274 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0005923 Cellular Component | bicellular tight junction | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0045216 Biological Process | cell-cell junction organization | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0050839 Molecular Function | cell adhesion molecule binding | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0098609 Biological Process | cell-cell adhesion | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0150105 Biological Process | protein localization to cell-cell junction | 272 / 316 | 86.1% | 98.9% of 275 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 255 / 316 | 80.7% | 92.7% of 275 | ≥80% support |
| Pfam | PF00595 | PDZ | 246 / 316 | 77.9% | 91.5% of 269 | ≥50% support |
| Pfam | PF00791 | ZU5 | 219 / 316 | 69.3% | 81.4% of 269 | ≥50% support |
| Pfam | PF00625 | Guanylate_kin — Guanylate kinase | 203 / 316 | 64.2% | 75.5% of 269 | ≥50% support |
| KEGG | K05701 | TJP1, ZO1 — Cytoskeleton proteins | 163 / 316 | 51.6% | 94.8% of 172 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Blastomussa wellsi | BRAKERLUSP00000014763.1 | XP_020608484.1 | tight junction protein ZO-1-like isoform X1 [Orbicella faveolata] | A0A0G2K2P5 Tight junction protein ZO-1 OS=Rattus norvegicus OX=10116 GN | JBrowse |
| Blastomussa wellsi | g2680.t1.1 | none | – | JBrowse |
