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This orthogroup contains 258 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 258 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10887 | DNA2/NAM7 HELICASE FAMILY | 208 / 258 | 80.6% | 98.1% of 212 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 214 / 258 | 83.0% | 97.3% of 220 | ≥80% support |
| GO | GO:0000184 Biological Process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 213 / 258 | 82.6% | 96.8% of 220 | ≥80% support |
| GO | GO:0003724 Molecular Function | RNA helicase activity | 213 / 258 | 82.6% | 96.8% of 220 | ≥80% support |
| Pfam | PF13087 | AAA_12 — AAA domain | 202 / 258 | 78.3% | 91.8% of 220 | ≥50% support |
| Pfam | PF13086 | AAA_11 — AAA domain | 183 / 258 | 70.9% | 83.2% of 220 | ≥50% support |
| Pfam | PF18141 | UPF1_1B_dom — RNA helicase UPF1, 1B domain | 171 / 258 | 66.3% | 77.7% of 220 | ≥50% support |
| Pfam | PF09416 | UPF1_Zn_bind — RNA helicase (UPF2 interacting domain) | 168 / 258 | 65.1% | 76.4% of 220 | ≥50% support |
| Pfam | PF04851 | ResIII — Type III restriction enzyme, res subunit | 159 / 258 | 61.6% | 72.3% of 220 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 183 / 258 | 70.9% | 83.2% of 220 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 183 / 258 | 70.9% | 83.2% of 220 | ≥50% support |
| GO | GO:0003723 Molecular Function | RNA binding | 169 / 258 | 65.5% | 76.8% of 220 | ≥50% support |
| GO | GO:0008270 Molecular Function | zinc ion binding | 169 / 258 | 65.5% | 76.8% of 220 | ≥50% support |
| GO | GO:0003677 Molecular Function | DNA binding | 160 / 258 | 62.0% | 72.7% of 220 | ≥50% support |
| GO | GO:0016787 Molecular Function | hydrolase activity | 159 / 258 | 61.6% | 72.3% of 220 | ≥50% support |
| KEGG | K14326 | UPF1, RENT1 — Messenger RNA biogenesis | 167 / 258 | 64.7% | 98.2% of 170 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Calvadosia cruxmelitensis | g430.t1 | XP_022799973.1 | insulin receptor substrate 1-like isoform X2 [Stylophora pistillata] | P35570 Insulin receptor substrate 1 OS=Rattus norvegicus OX=10116 G | JBrowse |
